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Clinical publications

Oticon Medical (before 2013 via Neurelec) has for over 30 years contributed to Cochlear Implant science within advanced medical technology and life sciences

Effects of unilateral cochlear implantation on balance control and sensory organisation in adult patients with profound hearing loss: a pilot study
Parietti-Winkler C, Lion A, Montaut-Verient B, Grosjean R & Gauchard GC. Biomed Research International, October 2015. 

This study conducted at the Nancy university hospital in France, evaluated the impact of cochlear implantation on balance control. Ten patients with severe-to-profound hearing loss (aged 55+/-20 years on average), who were candidates for a cochlear implantation received posturographic and vestibular evaluations before and after the surgery. The scores of the patients were compared to those of a group of ten normal hearing participants (63 ± 16 years), who received the same evaluations. Before cochlear implant surgery, the patients with severe-profound hearing loss showed a posturographic deficit compared to the normal-hearing participants. This deficit progressively diminished after cochlear implantation and scores were close to normal in the cochlear implant group about one year after implantation. Unilateral cochlear implantation can stimulate a mechanism of vestibular compensation, improving static and dynamic balance of recipients.


Improvement of Cognitive Function After Cochlear Implantation in Elderly Patients
Mosnier I, Bebear JP, Marx M, Fraysse B, Truy E, Lina-Granade G, Mondain M, Sterkers-Artières F, Bordure P, Robier A, Godey B, Meyer B, Frachet B, Poncet-Wallet C, Bouccara D & Sterkers O. JAMA Otolaryngol Head Neck Surg, May 2015.
This large multicentric study is a prospective longitudinal study involving ten different tertiary referral centers. Its objective was to analyze the relationship between cognitive function and hearing restoration with a cochlear implant in elderly patients. The evaluations were conducted in 94 patients (aged 65 to 85 years), including 29 Oticon Medical Digisonic SP patients, the most represented cochlear implant brand in this study. Included patients had profound, postlingual hearing loss and were evaluated before surgery and 6 and 12 months following cochlear implantation. The restoration of hearing was evaluated through speech perception scores in quiet and in noise and patients also received a detailed cognitive evaluation including six different tests evaluating attention, memory, orientation, executive function, mental flexibility, and fluency. Cochlear implantation had a positive impact on speech perception in quiet and in noise, on quality of life, and decreased the proportion of participants with responses indicating a depressive state. 80% among the patients with abnormal cognitive scores before cochlear implantation showed improved global cognitive function after cochlear implantation and improvements could be observed as early as 6 months after surgery.


A Retrospective Multicenter Study Comparing Speech Perception Outcomes for Bilateral Implantation and Bimodal Rehabilitation
Blamey PJ, Maat B, Başkent D, Mawman D, Burke E, Dillier N, Beynon A, Kleine-Punte A, Govaerts PJ, Skarzynski PH, Huber AM, Sterkers-Artières F, Van de Heyning P, O'Leary S, Fraysse B, Green K, Sterkers O, Venail F, Skarzynski H, Vincent C, Truy E, Dowell R, Bergeron F & Lazard DS. Ear & Hearing, August 2015.
This international multicentric study (15 international CI centers), analyzed retrospective data from 2247 patients (4 brands represented, including Oticon Medical Digisonic SP patients). The goal was to compare speech perception outcomes in three different groups of users: with a unilateral cochlear implant (CI/-), users with one cochlear implant and a hearing aid on the other side or bimodal users (CI/HA) and users with two CIs (CI/CI) or bilateral CI users. Results showed that speech intelligibility in quiet and in noise was significantly better in both bilateral (CI/CI) and bimodal (CI/HA), compared to unilateral CI users (CI/-). Bilateral CI users showed an improvement of +11% in quiet and +16% in noise compared to unilateral CI users. Bimodal (CI/HA) users showed improvements of +6% in quiet and +9% in noise. These data again establish the advantage of bilateral cochlear implantation compared to unilateral CI use. The authors conclude by saying that on average, for patients with very low preoperative performance, a second CI is likely to provide slightly better postoperative speech intelligibility outcomes than an additional HA.


Predictive factors of cochlear implant outcomes in the elderly
Mosnier I, Bebear JP, Marx M, Fraysse B, Truy E, Lina-Granade G, Mondain M, Sterkers-Artières F, Bordure P, Robier A, Godey B, Meyer B, Frachet B, Poncet C, Bouccara D & Sterkers O. Audiology and Neurotology, December 2013.
The goal of this prospective, longitudinal study performed in 10 tertiary referral centers in France, was to identify predictive factors of cochlear implant outcomes in patients aged 65 to 85 years. Ninety-four patients, among them 29 Oticon Medical cochlear implant users (30.8% of the study sample, Digisonic SP CI post-lingual adult users). Overall hearing and speech perception in quiet and noise were satisfying, demonstrating that CI in the elderly is an effective method to restore communication abilities. Better outcomes were observed when patients had spent less time deprived of hearing, when they presented functional residual hearing in the low frequencies or when they used a hearing aid before cochlear implantation. Cochlear implantation was proven to be safe and associated to rare surgical complications in this particular population. These results demonstrate the surgical feasibility and the rehabilitation efficiency of cochlear implantation in elderly patients.

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